Fluorous Technologies is a unit of Boron Specialties, LLC, 2301 Duss Avenue Suite 35, Ambridge, PA 15003

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FluoroFlash® -packed solid phase extraction cartridges

Fluorous solid phase extraction (F-SPE) is used for quick separations of reaction mixtures involving fluorous catalysts, reagents, protecting groups, tags, and scavengers (1-6).  F-SPE is used for quick separations of reaction mixtures involving FluoroFlash® tags, reagents, scavengers and catalysts.  The separation of fluorous compounds by F-SPE is a reliable and generic procedure that more greatly resembles filtration than chromatography.  The facile separation depends primarily on the presence or absence of a light fluorous tag, not polarity or other molecular features that control traditional chromatography.

A simple two-step separation of fluorous compounds involves the loading of a reaction mixture containing the fluorous-tagged molecule on to an F-SPE cartridge, washing the non-fluorous compounds away using a fluorophobic wash, then washing the fluorous compounds with a fluorophilic wash.  Please consult the F-SPE application note for a more detailed procedure.

FluoroFlash® SPE cartridges are pre-packed in a variety of formats with a proprietary fluorous silica gel.     

1. Zhang, W.; Curran, D. P. Tetrahedron 2006, 62, 11837–11865.

2. Curran, D. P. Handbook of Fluorous Chemistry, 2004, 101-155.

3. Zhang, W.; Curran, D. P.; Chen, C. H.-T. Tetrahedron, 2002, 58, 3871-3875.

4. Curran, D.; Lou, Z. Y. Green Chem. 2001, 3, G3-G7.

5. Zhang, Q.; Luo, Z.; Curran, D. P. J. Org. Chem. 2000, 65, 8866-8873.

6. Curran, D. P.; Hadida, S.; He, M. J. Org. Chem. 1997, 62, 6714-6715.


Please contact us for pricing and availability of the products below:

PRODUCT - FLUOROUS SPE CARTRIDGES

CATALOG NUMBER

FluoroFlash® SPE Cartridges, 2 grams, 8 cc tube (2)  

x801-0027S-2

FluoroFlash® SPE Cartridges, 2 grams, 8 cc tube (5)  

x801-0027S-5

FluoroFlash® SPE Cartridges, 2 grams, 8 cc tube (20)  

x801-0027S-20

FluoroFlash® SPE Cartridges, 5 grams, 10 cc tube (2)  

x801-0058S-2

FluoroFlash® SPE Cartridges, 5 grams, 10 cc tube (10)  

x801-0058S-10

FluoroFlash® SPE Cartridges, 10 grams, 60 cc tube (1)  

x801-0109S-1

FluoroFlash® SPE Cartridges, 10 grams, 60 cc tube (5)  

x801-0109S-5

FluoroFlash® SPE Cartridges, 20 grams, 60 cc tube (1)  

x801-0209S-1

FluoroFlash® SPE Cartridges, 20 grams, 60 cc tube (5)  

x801-0209S-5

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