Tag Archives: surfactant

Fluorous surfactants as new spermicidal contraceptives?

Of late, fluorous surfactants (detergents) have been¬†increasingly making their way into various biomedical and pharmaceutical applications. Another new addition to this family is a recent patent (WO2009/026375) filed by Lehigh University that describes the spermicidal and microbicidal properties of fluorous … Continue reading

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Fluorous Linker

If you read the previous post where we looked at a recent review on fluorous linkers, one of the nits picked was that the review really didn’t look at linkers as is in the title, since the fluorous domains on … Continue reading

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Are fluorinated surfactants less cytotoxic?

As per a recent communication (New J. Chem., 2008, 32, 2169), this indeed appears to be the case, at least for single-tailed glucopyranoside surfactants compared to their hydrocarbon counterparts.¬† Non-ionic surfactants of this type are of interest in biomedical applications, … Continue reading

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Biphasic Biocatalysis By Adding Fluorosurfactants

A little more than a year ago, we published a post describing Prof. Neil Thomas’ work in fluorous biphasic biocatalysis.¬† The key to this was that an enzyme, in this case ?-chymotrypsin mediated transesterification, could be rendered fluorous through non-covalent … Continue reading

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Fluorous Surfactants – II

Another interesting design of fluorosurfactants has recently been reported by Krafft et al. (Tetrahedron 64: 2008, 522-528). In the communication they described the synthesis of a triphilic, Y-shaped molecular surfactant that comprises three chains, viz., a perfluoroalkyl, a hydrocarbon and … Continue reading

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