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Tag Archives: surfactant
Fluorous surfactants as new spermicidal contraceptives?
Of late, fluorous surfactants (detergents) have been increasingly making their way into various biomedical and pharmaceutical applications. Another new addition to this family is a recent patent (WO2009/026375) filed by Lehigh University that describes the spermicidal and microbicidal properties of fluorous … Continue reading
Fluorous Linker
If you read the previous post where we looked at a recent review on fluorous linkers, one of the nits picked was that the review really didn’t look at linkers as is in the title, since the fluorous domains on … Continue reading
Are fluorinated surfactants less cytotoxic?
As per a recent communication (New J. Chem., 2008, 32, 2169), this indeed appears to be the case, at least for single-tailed glucopyranoside surfactants compared to their hydrocarbon counterparts. Non-ionic surfactants of this type are of interest in biomedical applications, … Continue reading
Posted in Assorted Fluorous Items
Tagged drug delivery, Materials, surfactant, toxocity
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Biphasic Biocatalysis By Adding Fluorosurfactants
A little more than a year ago, we published a post describing Prof. Neil Thomas’ work in fluorous biphasic biocatalysis. The key to this was that an enzyme, in this case ?-chymotrypsin mediated transesterification, could be rendered fluorous through non-covalent … Continue reading
Fluorous Surfactants – II
Another interesting design of fluorosurfactants has recently been reported by Krafft et al. (Tetrahedron 64: 2008, 522-528). In the communication they described the synthesis of a triphilic, Y-shaped molecular surfactant that comprises three chains, viz., a perfluoroalkyl, a hydrocarbon and … Continue reading