Tag Archives: oligosaccharide

PTFE Immobilization of Fluorous Tagged Oligosaccharides

A very interesting paper with Prof. Mamoru Mizuno as the corresponding author is now available as an accepted manuscript in Bioorganic & Medicinal Chemistry Letters.  The work presented is the recognition of influenza virus by oligosaccharides immobilized on a polytetrafluoroethylene … Continue reading

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Fluorous Protecting Groups in Oligosaccharide Synthesis

The regular reader of F-Blog will know that the fluorous-assisted synthesis of oligosaccharides is one of the best applications of fluorous techniques.  Fluorous tags and separations, primarily fluorous solid phase extraction (FSPE), have been used in a number of different … Continue reading

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Fluorous Mixture Synthesis of Cucurbitosides

In 2008 the Takeuchi group at Niigata University reported the total synthesis of cucurbitoside A, one of a series partially acylated phenolic glycosides.  The cucurbitosides are found in the seeds of squashes and pumpkins of the genus Cucurbita.  Water extracts … Continue reading

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Reverse Orthogonal Oligosaccharide Synthesis

A just published Advance Article in Chemical Communications from Prof. Alexei Demchenko at the Univ of Missouri-St. Louis describes a strategy for oligosaccharide construction using what they term a reverse orthogonal strategy.  As we have noted here in F-Blog, and … Continue reading

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Fluorous User Interview: Renpeng Liu

Dr. Renpeng Liu is currently a postdoctoral researcher in the field of glycomics at Emory University.  Before that he was at the Eshelman School of Pharmacy at the University of North Carolina working on the synthesis of heparans which resulted … Continue reading

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