Tag Archives: NIMS

Using Fluorous Tags to Mass Differentiate Stereospecific Reactions

Trent Northen and co-workers have been using fluorous immobilization in conjunction with nanostructure initiated mass spec (NIMS) in a number of different applications.  Dr. Northen was one of the inventors of NIMS while working in Gary Siuzdak’s labs at The … Continue reading

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Glycan Arrays Using Hydrophobic Tags

One of the areas of research which we identified as growth areas for fluorous chemistry in 2011 was glycomics.  Fluorous methods have already been shown to be highly useful in the synthesis, purification, and immobilization of carbohydrates.  What remains then … Continue reading

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NIMS and Nimzyme

In 2007, Prof. Gary Siuzdak and co-workers at The Scripps Research Institute introduced Nanostructure-Initiator mass spectrometry(NIMS) as a new surface-based mass analysis method. Just available online is a Analytical Chemistry “Feature” on NIMS describing its attributes, capabilities, and applications, primarily in … Continue reading

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H1N1, Carbohydrates, and Microarrays

The study of carbohydrates is of great interest since they are one of the most abundant of cell surface molecules and are, therefore, important players in many intercellular interactions.  An example from current events which illustrates the role of carbohydrates … Continue reading

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Fluorous at ASMS

Fluorous techniques for biological sample enrichment will be on display at the 57th ASMS Conference on Mass Spectrometry, to be held from May 31 to June 4, 2009 at the Pennsylvania Convention Center in Philadelphia, PA.   Here’s a list of … Continue reading

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