Tag Archives: Microwave

Fluorous and Microwave

In Fluorous Technologies’ April Technical Newsletter we highlighted some recent examples from the literature demonstrating the use of fluorous methods in conjunction with other technologies.  One of the other technologies was microwave heating.  While we only showed one example in … Continue reading

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Parallel Benzodiazpinedione Synthesis

A group of researchers led by Prof. Bing Yan have just published their use of fluorous tags in benzodiazopinedione synthesis in J. Comb. Chem. The general reaction scheme is shown below.   The researchers chose to use a fluorous sulfonyl tag … Continue reading

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Multi-Component Reactions Using Fluorous tags

An J. Combi. Chem. ASAP paper from the Center for Chemical Methodologies and Library Design at the University of Pittsburgh describes the synthesis of a 90-member fused piperazinedione library.  The key first step in the synthesis is a multi-component reaction … Continue reading

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Microwave Assisted Fluorous Synthesis of Oligothiophenes

Prof. Michael Turner and co-workers at the University of Manchester have recently described a fluorous synthesis of oligothiophenes. Their interest in oligothiophenes is in their utility as organic semiconductors in thin film transistor devices. As noted in the report, oligothiophenes … Continue reading

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Library Synthesis using fluorous sulfonate tag

Recently, Bing Yan etc. published a paper (J. Comb. Chem. 2008, asap) on the synthesis of 2-aryl-substituted 4-thiazolidinone and 4-thiazinanone libraries as drug candidates. Fluorous sulfonate tag 3 was introduced and performed 2 functions during the syntheses: as a phase … Continue reading

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