Tag Archives: Microarray

Glycosphingolipid Analysis using Fluorous Tags

Glycosphingolipids (GSLs) are an important class of molecules which have been associated with several cellular functions including antigen activity, cell adhesion, and signal transduction.  As the name suggests these molecules consist of a glycan portion and a lipid portion.  Study … Continue reading

Posted in FSPE, Life Science Applications, Microarray, Proteomics | Tagged , , , | Comments Off

H1N1, Carbohydrates, and Microarrays

The study of carbohydrates is of great interest since they are one of the most abundant of cell surface molecules and are, therefore, important players in many intercellular interactions.  An example from current events which illustrates the role of carbohydrates … Continue reading

Posted in Biomolecule Synthesis, Carbohydrates, Life Science Applications, Microarray | Tagged , , , | Comments Off

Fluorous Peptide Microarrays

Microarrays which are formed through fluorous immobilization of probes have been reported in the literature for small molecules and carbohydrates.  At ISoFT ’09, we reported the synthesis, purification, and immobilization of fluorous tagged peptides.  This work, conducted jointly by scientists … Continue reading

Posted in Biomolecule Synthesis, Life Science Applications, Microarray, Peptides | Tagged , , , , | Comments Off

ISoFT’09, Monday Report

Last night was the real beginning of the ISoFT’09 portion of the conference with the ISoFT Award session.  The session was held in the evening with no other concurrent sessions.  To begin the session we were treated to some sort … Continue reading

Posted in Biomolecule Synthesis, Carbohydrates, Life Science Applications, Separation Techniques, Small Molecule Synthesis | Tagged , , , , | Comments Off

Click! Fluorous Immobilization of Probes

The immobilization of fluorous tagged substrates to a fluorous modified glass slide has now been demonstrated by several different research groups for the formation of microarrays.  Fluorous based microarrays offer several advantages including low and uniform background fluorescence, low non-specific … Continue reading

Posted in Life Science Applications, Microarray | Tagged , , , , | Comments Off