Tag Archives: metabolomics

Biomolecule Detection Using Fluorous Separations

The Yamaguchi group at Fukuoka University has published a new review of their work in biomolecule detection in J. Chromatography B.  They have been focused on the use of fluorescence derivatization and/or fluorous enrichment for the detection of molecules of … Continue reading

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Fluorous Derivatization for Quantification of Drugs in Human Plasma

Researchers at Fukuoka University have over the past two years published a series of papers describing their work using fluorous methods for detection of various metabolites, both endogeneous and exogenous, from biological fluids.  One of the papers was to use … Continue reading

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NIMS and Nimzyme

In 2007, Prof. Gary Siuzdak and co-workers at The Scripps Research Institute introduced Nanostructure-Initiator mass spectrometry(NIMS) as a new surface-based mass analysis method. Just available online is a Analytical Chemistry “Feature” on NIMS describing its attributes, capabilities, and applications, primarily in … Continue reading

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Fluorous Scavenging in Metabolomics

In proteomics and metabolomics applications sensitivity is highly important since many of the most interesting proteins and metabolites are present in low concentrations.  In addition, some metabolites such as carboxylic acids do not contain functionality which is fluorescent or highly … Continue reading

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