Tag Archives: Isotope chemistry

More Fluorous Isotope Chemistry

Posted on September 10, 2010 by Marv

Right on the heels of our September 2010 Technical Newsletter that highlighted the use of fluorous techniques in isotope chemistry comes a US Patent Application from GE Healthcare claiming the use of perfluoro-aryliodonium salts for the preparation of 18F aromatics. … Continue reading →

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Isotope Chemistry Newsletter

Posted on September 8, 2010 by Jeff

The September issue of our Fluorous Technical Newsletter covers the broad spectrum of fluorous techniques used in isotope chemistry.  Fast, effective solution phase fluorous separations accelerate synthesis and purification in time sensitive applications.  Read more about how fluorous can improve … Continue reading →

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Fluorous in 18F Substitution

Posted on January 20, 2010 by Marv

About one year ago, a report from the Gouverneur lab in Oxford reported the use of fluorous sulfonates as precursors to 18F imaging agents.  Nucleophilic displacement of the fluorous sulfonate by 18F anion provided the desired compounds as shown below.  … Continue reading →

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Fluorous tagged Carbohydrate for Liver Imaging

Posted on July 2, 2009 by Marv

In the last year, they’re have been several papers using fluorous tags and methods in either the synthesis and purification of radioimaging agents, as an integral part of the imaging agent, or both. These include the production of 18F agents … Continue reading →

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FIT for MRI

Posted on June 4, 2009 by Marv

As just about everyone knows, magnetic resonance imaging (MRI) is a very important diagnostic technique in medicine.  1H MRI, or NMR as we chemists know it, is the technique used clinically and is a noninvasive technique which provides in vivo … Continue reading →

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