Tag Archives: immobilization

Fluorous Tags for Immobilization

Posted on December 6, 2011 by Marv

As the regular reader of F-Blog knows, fluorous tags can be used for purification, enrichment, and immobilization.  Of those three areas fluorous immobilization is the newest and probably the least established at this point.  While there has been plenty of … Continue reading →

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PTFE Immobilization of Fluorous Tagged Oligosaccharides

Posted on December 1, 2011 by Marv

A very interesting paper with Prof. Mamoru Mizuno as the corresponding author is now available as an accepted manuscript in Bioorganic & Medicinal Chemistry Letters.  The work presented is the recognition of influenza virus by oligosaccharides immobilized on a polytetrafluoroethylene … Continue reading →

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Fluorous PALs for Immobilization

Posted on November 4, 2011 by Marv

Over the last couple of years there have been several reports by various research groups describing fluorous photoaffinity labeling agents (PALs).  These molecules have been aziridines with a fluorous tag attached such that upon exposure to UV light a carbene … Continue reading →

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Upon Further Review

Posted on April 20, 2011 by Marv

Over the past month or two several reviews have been published which mention or have fluorous sections within them.  None of these reviews are dedicated to fluorous techniques, but rather to other topics where fluorous methods are just a part. … Continue reading →

Posted in Assorted Fluorous Items, Biomolecule Synthesis, Life Science Applications, Microarray, Proteomics, Small Molecule Synthesis | Tagged , , , , | Comments Off

Glycan Arrays with Direct MS Readout

Posted on November 18, 2010 by Marv

Immobilization of fluorous tagged molecules onto a fluorous surface has been conducted by several groups for the formation of microarrays.  Generally the surface has been a fluorous modified glass slide.  Solutions containing the fluorous tagged probe are spotted on the … Continue reading →

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