Tag Archives: enrichment

FLAC-Fluorous Labeling Assisted Capture

Posted on November 20, 2009 by Marv

The enrichment of peptide subsets is an important part of proteomics in order to simplify sample complexity or to target specific posttranslational modifications for study.  A number of ways for enrichment are known mostly based on affinity chromatography with biotin-avidin … Continue reading →

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Photoaffinity Labeling Reagents with Fluorous Tags

Posted on November 6, 2009 by Marv

Photoaffinity labeling is a technique in proteomics by which to identify ligand binding sites in proteins or to study protein:protein interactions.  The label generally consists of three parts; a) a protein recognition or functional group reactive portion, b) a photoactive … Continue reading →

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Fluorous at ASMS

Posted on April 28, 2009 by Jeff

Fluorous techniques for biological sample enrichment will be on display at the 57th ASMS Conference on Mass Spectrometry, to be held from May 31 to June 4, 2009 at the Pennsylvania Convention Center in Philadelphia, PA.   Here’s a list of … Continue reading →

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Proteomics Review

Posted on April 21, 2009 by Marv

Many of the readers of F-Blog may not be familiar with field of proteomics, since we have a tendency to be more chemistry-centric, but it’s a fascinating area and fast moving area of research.  Just available online is a short … Continue reading →

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Glycoproteomics

Posted on March 16, 2009 by Marv

In February, the Journal of Proteome Research published a special issue dedicated to glycoproteomics.  Glycosylation is one of the many posttranslational modifications (PTMs) that proteins can undergo after biosynthesis.  Others include ubiquitination, phosphorylation, acylation, deacetylation, glutamylation, etc.  Given all the … Continue reading →

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