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Tag Archives: enrichment
Fluorous Photoaffinity Labeling
Photoaffinity labeling reagents is a valuable way by which to study the interactions between two molecular entities. Often times this is a ligand and it’s receptor. The strategy is to attach the photolabel to a ligand, incubate with it’s binding … Continue reading
Posted in Life Science Applications, Proteomics
Tagged enrichment, photoaffinity, Proteomics
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Fluorous Enrichment for PTM Detection
One of the challenges in proteomics is the detection and quantitation of low level peptide species. Often times these are specific posttranslational modifications (PTMs) of proteins which are present only in small amounts but can have big biological effects. As … Continue reading
Posted in Life Science Applications, Proteomics
Tagged enrichment, FSPE, Kim, Konkuk University, nitration, Proteomics, PTM
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Fluorous Proteomics: Amine Tagging
Since the introduction of fluorous techniques in protoemics in 2005 by Eric Peters and co-workers at the Genomics Institute of the Novartis Research Foundation, several groups have used fluorous methods for the enrichment of specific peptide subsets. Fluorous methods represent … Continue reading
Posted in Assorted Fluorous Items, FSPE, Life Science Applications, Proteomics, Separation Techniques
Tagged amine tagging, enrichment, Proteomics
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Glycosphingolipid Analysis using Fluorous Tags
Glycosphingolipids (GSLs) are an important class of molecules which have been associated with several cellular functions including antigen activity, cell adhesion, and signal transduction. As the name suggests these molecules consist of a glycan portion and a lipid portion. Study … Continue reading
Posted in FSPE, Life Science Applications, Microarray, Proteomics
Tagged enrichment, glycomics, glycosphingolipids, mass spec, Microarray
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