Tag Archives: DOS

Diversity Oriented Synthesis Update

Posted on January 13, 2009 by Marv

Back in November, we published a F-Blog post which highlighted the work of Prof. Adam Nelson which described his use of a fluorous linker and olefin metathesis chemistry in diversity-oriented synthesis (DOS).  The library produced had an unprecedented level of … Continue reading →

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Diversity Oriented Synthesis vs. Combinatorial Chemistry

Posted on December 9, 2008 by Marv

In the last several weeks, we’ve published a couple of posts where researchers used fluorous techniques in the production of diversity oriented synthesis (DOS) libraries. As we have noted DOS libraries are particularly well-suited for fluorous techniques since fluorous purification … Continue reading →

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More Fluorous Diversity-Oriented Synthesis

Posted on November 21, 2008 by Marv

Not too long ago F-Blog published a post describing some of the work of Prof. Adam Nelson’s group at the University of Leeds using fluorous tags in cascade olefin metathesis reactions. The reactions described in that report built a number … Continue reading →

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Antibacterial Agent Discovery

Posted on November 11, 2008 by Marv

Researchers from various organizations led by Dave Spring at Cambridge University have recently communicated (Chem. Comm. 2008, 4962) their efforts at discovering new antibacterial agents. In particular they targeted agents that would display activity against strains of epidemic MRSA (EMRSA). … Continue reading →

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