Tag Archives: Diversity Oriented Synthesis

Diversity Oriented Synthesis vs. Combinatorial Chemistry

In the last several weeks, we’ve published a couple of posts where researchers used fluorous techniques in the production of diversity oriented synthesis (DOS) libraries. As we have noted DOS libraries are particularly well-suited for fluorous techniques since fluorous purification … Continue reading

Posted in Small Molecule Synthesis | Tagged , | Comments Off

More Fluorous Diversity-Oriented Synthesis

Not too long ago F-Blog published a post describing some of the work of Prof. Adam Nelson’s group at the University of Leeds using fluorous tags in cascade olefin metathesis reactions. The reactions described in that report built a number … Continue reading

Posted in Library Synthesis | Tagged , , , | Comments Off

Antibacterial Agent Discovery

Researchers from various organizations led by Dave Spring at Cambridge University have recently communicated (Chem. Comm. 2008, 4962) their efforts at discovering new antibacterial agents. In particular they targeted agents that would display activity against strains of epidemic MRSA (EMRSA). … Continue reading

Posted in Library Synthesis, Small Molecule Synthesis | Tagged , | Comments Off