Tag Archives: Curran

Orthogonal Fluorous Mixture Synthesis (FMS)

University of Pittsburgh Professor and Fluorous Technologies, Inc. founder, Dennis Curran, has over the last several years dedicated a good portion of his research to fluorous mixture synthesis (FMS).  In FMS, libraries or isomers of compounds can be made in … Continue reading

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NMR Analysis of Natural Products with Multiple Stereocenters

Over the last several years, Prof. Dennis Curran’s group has been synthesizing various natural products with multiple stereocenters using fluorous mixture synthesis (FMS).  Many of these natural products have been ones with stereocenters distal from each other.  What Prof. Curran … Continue reading

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Total Synthesis of (+)-Chamuvarinin

An ASAP paper in Organic Letters from the University of St. Andrews describing the synthesis and stereochemical assignment of (+)-chamuvarinin is now accessible online.  Chamuvarinin was isolated in 2004 from extracts of a West African plant, Uvaria chamae, which is … Continue reading

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Fluorous Host-Guest Chemistry and Transport

The use of a fluorous phase as a liquid membrane has been applied in several multiphasic reactions, primarily fluorous triphasic and phase-vanishing reactions.  In both cases, the fluorous liquid phase is used as a barrier separating two other phases, one … Continue reading

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