Tag Archives: Catalysis

Fluorous Triazole Catalysis

The first incarnation of fluorous tagging, separation, and recovery was in catalysis.  In general, ligands which are used in metal catalyzed reactions are fluorous tagged, complexed to the appropriate metal, then used as catalysts for the reaction.  The ligands and/or … Continue reading

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Perfluoro-tagged palladium nanoparticles

A recent communication in Org. Biomol. Chem. by Prof. Cacchi and coworkers describes new perfluoro-tagged palladim nanoparticles for alkynylation of aryl halides.  They initially prepared perfluoro-tagged palladium nanoparticles supported on fluorous silica gel (Pdnp-A/FSG), and tested the catalyst in alkynylation … Continue reading

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Perfluoroalkane-tagged chiral auxiliary – application to stereoselective synthesis of a beta-amino acid building block

The advantage of tagging organic compounds or biomolecules with perfluoroalkane groups has led to the publication of several research articles by many. Extending this to the chiral auxillaries is no exception. Several such fluorous oxazolidinone based chiral auxillaries have been … Continue reading

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Catalytic Triphasic Reaction

Back in the early part of this decade, University of Pittsburgh professor and FTI founder, Dennis Curran, published the first example of a fluorous triphasic reaction.  The triphasic reaction as originally published was conducted in a U-tube with a fluorous … Continue reading

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Fluorous Lewis acids and phase transfer catalysis

That’s the title of a recent review published in the journal Molecular Diversity.  The review covers in good detail all of the work conducted using fluorous Lewis acids, primarily metal perfluorosulfonates  such as Yb(OSO2C8F17)3, in catalyzing various reactions.  Basically, any … Continue reading

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