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Tag Archives: Carbohydrates
July 2011 Technical Newsletter
This morning FTI launched our July 2011 Technical Newsletter whose theme is fluorous techniques in carbohydrate synthesis. The Technical Newsletter is distributed by email about every six weeks or so and is designed to complement F-Blog. While F-Blog highlights items of interest … Continue reading
Enzymatic Fluorous Tagging
One of the strengths of fluorous methods is the high degree of chemical compatibility. Due to the strength of the C-F bond fluorous tags are essentially inert to most chemical conditions. Anionic, cationic, radical, organometallic, you name it. Whatever conditions … Continue reading
Posted in Assorted Fluorous Items, Biomolecule Synthesis, Carbohydrates
Tagged Carbohydrates, enzymatic, tagging
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Fluorous Phosphate Protecting Group
A second post in a row on phosphate chemistry which is a new record for F-Blog. In this instance, however, we’re not discussing the enrichment of phsphorylated peptides, but the synthesis of phosphorylated carbohydrates. As discussed in the last post … Continue reading
Posted in Assorted Fluorous Items, Biomolecule Synthesis, Carbohydrates, FSPE, Separation Techniques
Tagged Carbohydrates, FSPE, Nicola Pohl, phosphorylation, protecting groups
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New Heavy Fluorous Tag for Synthesis
Researchers at the Noguchi Institute in Tokyo, led by Profs. Miura, Inazu, and Mizuno, have been using fluorous methods for the synthesis of peptides and carbohydrates for quite some time. Most of the time their approach has been to use … Continue reading
Posted in Biomolecule Synthesis, Carbohydrates, Liquid-Liquid Extraction (LLE)
Tagged Carbohydrates, FLLE, Mizuno
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Oligosaccharide Catch and Release
The synthesis of oligosaccharides is not easy when compared to to other oligomeric biomolecules such as oligonucleotides and peptides. There’s a number of reasons for this, but primarily it comes down to one thing: complexity. For example, DNA is made … Continue reading
Posted in Biomolecule Synthesis, Carbohydrates, FSPE, Separation Techniques
Tagged Carbohydrates, catch and release, FSPE, hydrazine
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