Tag Archives: carbohydrate

Fluorous tagged Carbohydrate for Liver Imaging

Posted on July 2, 2009 by Marv

In the last year, they’re have been several papers using fluorous tags and methods in either the synthesis and purification of radioimaging agents, as an integral part of the imaging agent, or both. These include the production of 18F agents … Continue reading →

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New Fluorous Protecting Group for Carbohydrate Synthesis

Posted on February 27, 2009 by Marv

Protecting group chemistry is of vital importance in synthetic chemistry to ensure that reactions occur where and when you want during a synthesis.  The more functionality a target molecules has, the more protecting groups are needed.  The more protecting groups … Continue reading →

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Carbohydrate Synthesis using Fluorous Tags and Separations

Posted on February 19, 2009 by Marv

Over the last several years, fluorous methods in oligosaccharide chemistry has probably been one of the more active areas of fluorous chemistry with various strategies being employed.  (Visit our website for a fuller explanation of methods to biomolecule synthesis.) These … Continue reading →

Posted in Biomolecule Synthesis, Carbohydrates, FSPE, Separation Techniques | Tagged , , , , | 8 Comments

Colorimetric Monitoring in Carbohydrate Synthesis

Posted on February 4, 2009 by Marv

Beyond small molecule chemistry, some of the best uses to date of fluorous techniques has been in carbohydrate chemistry.  Prof. Nicola Pohl at Iowa State University has been one of the most active researchers in fluorous carbohydrate chemistry and fluorous … Continue reading →

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Fluorous Nanostructure-Initiator MS (NIMS)

Posted on March 8, 2008 by Marv

Just published online is a very interesting PNAS paper from Profs. Chi-Huey Wong and Gary Siuzdak at Scripps describing their work in developing enzyme activity assays using MS detection. Specifically, they have extended the scope of the nanostructure-initiator MS (NIMS) … Continue reading →

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