Tag Archives: biphasic catalysis

Fluorous Thio-Ether Phosphines for Biphasic Catalysis

Late last year a paper in Synthesis from Martin and co-workers from Universidad Nacional Autónama de Mexico described the synthesis of some thio-ether phosphines.  The compounds shown below were prepared and included 4 fluorous analogs; 3, 5, 7, and 8, … Continue reading

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Fluorous Solid-Phase Supported Catalysis

The previous post was centered around a new publication from Alison Stuart’s group describing a new fluorous Pd pincer catalyst for Heck reactions.  The catalyst was recovered by fluorous solid phase extraction (FSPE) and recycled over several runs.  Mentioned in … Continue reading

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Fluorous Silica Gel Supported Pd Nanoparticles

The genesis of fluorous chemistry in the early 90′s was biphasic catalysis where a fluorous liquid phase was used as a support for fluorous catalysts.  The concept is still being utilized today although most of the time in slightly different … Continue reading

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Solvation-Mediated Biphasic Catalysis

Solvophobicity is a term that we’ve used often here on F-Blog to describe many of the behaviors of fluorous molecules in relation to partitioning.  While terms such as “fluorous affinity” are also used, it’s not really technically correct.  While dipole … Continue reading

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Fluorous molecules and carbon dioxide

A recent article in Journal of Supercritical Fluids from groups in Japan, China, and Taiwan describes the use of CO2 to tune fluorous Pd catalysts in Heck and Sonagashira reactions.  The researchers conducted a simple Heck reaction (iodobenzene and methyl … Continue reading

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