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Tag Archives: biphasic catalysis
Solvation-Mediated Biphasic Catalysis
Solvophobicity is a term that we’ve used often here on F-Blog to describe many of the behaviors of fluorous molecules in relation to partitioning. While terms such as “fluorous affinity” are also used, it’s not really technically correct. While dipole … Continue reading
Posted in Liquid-Liquid Extraction (LLE), Separation Techniques
Tagged biphasic catalysis, distannoxane, FLLE, solvophobicity
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Fluorous molecules and carbon dioxide
A recent article in Journal of Supercritical Fluids from groups in Japan, China, and Taiwan describes the use of CO2 to tune fluorous Pd catalysts in Heck and Sonagashira reactions. The researchers conducted a simple Heck reaction (iodobenzene and methyl … Continue reading
Posted in Liquid-Liquid Extraction (LLE), Separation Techniques, Small Molecule Synthesis
Tagged biphasic catalysis, CO2, Heck reaction, Pd catalysis, Thermomorphic
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Aqueous Microdroplets, ISoFT ’09 and Beyond
One of the more interesting talks that was not mentioned in the ISoFT ’09 posts of last week was one from Dr. Roger Nassar of RainDance Technologies using microdroplet technology to provide a unique platform for high-throughput screening. The technology … Continue reading
Posted in Small Molecule Synthesis
Tagged biphasic catalysis, ISoFT'09, microdroplet, microreactor, Pd, Suzuki-Miyaura coupling
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Fluorous Supported Photooxidation
The immobilization of fluorous tagged catalysts on fluorous silica gel has been utilized many times to provide an easily recoverable and reusable catalyst. The system is a version of biphasic catalysis where the fluorous liquid phase is replaced by a … Continue reading
Posted in Assorted Fluorous Items
Tagged biphasic catalysis, flavin, fluorous silica gel, photooxidation
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Fluorous Aryl and Alkyl iodine(III) Dichlorides as Recyclable Chlorinating Reagents
In a recent paper from Gladysz (JOC 2009 ASAP), several fluorous aryl and alkyl iodine(III) dichlorides were synthesized and tested as recyclable chlorinating reagents. Aryl iodine(III) dichlorides were synthesized by bubbling chlorine gas through hexane solutions of corresponding aryl iodide. The … Continue reading