Category Archives: Scavengers and Reagents

Fluorous Scavenging for Radioimaging Agent Production

Prof. John Valliant’s group at McMaster University has been one of the most active researchers in the application of fluorous techniques to the production of radioimaging agents.  Most of the work to date has used fluorous aryl tins as precursor … Continue reading

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Fluorous Technologies, Inc. Newsletter: Small Molecule Synthesis

This morning FTI launched our May 2011 Technical Newsletter whose theme is fluorous techniques in small molecule synthesis.  The Technical Newsletter is distributed by email about every six weeks or so and is designed to complement F-Blog.  While F-Blog highlights … Continue reading

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Mitsunobu Reaction: Fluorous vs. MPEG

Anyone which has conducted some organic synthesis has probably conducted Mitsunobu reactions for the formation of ethers, esters, or sulfonamides.  It’s really a great reaction which is conducted under mild conditions.  Usually the two substrates are an alcohol as the … Continue reading

Posted in FSPE, Liquid-Liquid Extraction (LLE), Scavengers and Reagents, Separation Techniques, Small Molecule Synthesis | Tagged , , , , | 1 Comment

Fluorous Triazole Organocatalyst

The Cai group at Nanjing University have been ardently pursuing various fluorous catalyst and tagging methods for small molecule synthesis.  They’ve added to their body of work with a new publication in J. Fluorine. Chem. describing the use and recovery … Continue reading

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Air-Stable Fluorinating Reagent

A recent publication In J. Am. Chem. Soc. described the preparation, properties, and reaction of a new deoxyfluorinating agent shown below.  The researchers have dubbed this new reagent Fluolead.  Deoxyfluorination is a very useful reaction, particularly in medicinal chemistry, where … Continue reading

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