Category Archives: Mixture Synthesis

Orthogonal Fluorous Mixture Synthesis (FMS)

University of Pittsburgh Professor and Fluorous Technologies, Inc. founder, Dennis Curran, has over the last several years dedicated a good portion of his research to fluorous mixture synthesis (FMS).  In FMS, libraries or isomers of compounds can be made in … Continue reading

Posted in Assorted Fluorous Items, F HPLC, Mixture Synthesis, Separation Techniques, Small Molecule Synthesis | Tagged , , , | Comments Off

NMR Analysis of Natural Products with Multiple Stereocenters

Over the last several years, Prof. Dennis Curran’s group has been synthesizing various natural products with multiple stereocenters using fluorous mixture synthesis (FMS).  Many of these natural products have been ones with stereocenters distal from each other.  What Prof. Curran … Continue reading

Posted in F HPLC, Mixture Synthesis, Small Molecule Synthesis | Tagged , , , | Comments Off

Fluorous Technologies, Inc. Newsletter: Small Molecule Synthesis

This morning FTI launched our May 2011 Technical Newsletter whose theme is fluorous techniques in small molecule synthesis.  The Technical Newsletter is distributed by email about every six weeks or so and is designed to complement F-Blog.  While F-Blog highlights … Continue reading

Posted in Assorted Fluorous Items, Library Synthesis, Mixture Synthesis, Scavengers and Reagents, Small Molecule Synthesis | Tagged , | Comments Off

Total Synthesis of (+)-Chamuvarinin

An ASAP paper in Organic Letters from the University of St. Andrews describing the synthesis and stereochemical assignment of (+)-chamuvarinin is now accessible online.  Chamuvarinin was isolated in 2004 from extracts of a West African plant, Uvaria chamae, which is … Continue reading

Posted in F HPLC, Mixture Synthesis, Small Molecule Synthesis | Tagged , , , | Comments Off

Encode Information to your Molecules with Fluorous Tags

Fluorous tags, like the amine protecting group F17 Boc-ON, provide a lot of functions.  They can be attached and removed just like non-fluorous tags and similarly protect functional groups.  While attached to your molecule, the fluorous tag also allows for … Continue reading

Posted in F HPLC, Mixture Synthesis | Tagged , , | Comments Off