Category Archives: Oligonucleotides

Synthetic Oligonucleotide Purification by Polymerization

Posted on August 3, 2010 by Marv

An ASAP Organic Letters paper from Fang and Fueangfung at Michigan Technological University describes their work in using phase tags for the purification of synthetic oligonucleotides.  In this case the phase tag is a polymerizable tag attached to the terminal … Continue reading →

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DNA Detection Using Gold Nanoparticles and Fluorous tags

Posted on November 13, 2009 by Marv

A very interesting Angewandte Chemie Int. Ed. Early View paper from Prof. Jin Zhu at Nanjing University is now available online that describes the use of gold nanoparticles (AuNPs) and fluorous tags for DNA detection.  The researchers have developed a … Continue reading →

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ISoFT ’09, Tuesday Report

Posted on August 26, 2009 by Marv

Today was the big day for ISoFT’09 with lectures starting at 8 AM and lasting until 5 PM.  In total there was 18 talks with topics ranging from small molecule chemistry, materials, oligonucleotides, carbohydrates, sensors, and carbohydrates.  With that many … Continue reading →

Posted in Biomolecule Synthesis, Carbohydrates, Life Science Applications, Oligonucleotides, Separation Techniques, Small Molecule Synthesis | Tagged , , , , , | 3 Comments

2009 Berry & Associates catalog

Posted on July 6, 2009 by Marv

Fluorous techniques have been used by numerous research groups in the synthesis and purification of oligonucleotides with impressive results particularly with long oligos consisting of >50 nucleotides. FTI’s partner in oligonucleotide chemistry is Berry & Associates who have developed a … Continue reading →

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Latest Review on Fluorous Chemistry

Posted on January 15, 2009 by Marv

Just available online is a new review from Prof. Wei Zhang of UMass-Boston detailing the use of fluorous tags in synthesis.  The title of the review is “Fluorous Linker-Facilitated Chemical Synthesis” and convers the use of fluorous tags in small … Continue reading →

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