Category Archives: FSPE

Parallel Synthesis of O-aryloxyamines

Posted on July 27, 2010 by Marv

Aryloxyamines are an interesting class of compounds which have been used in a variety of applications.  They are excellent intermediates for the synthesis of a number of biologically active heterocycles.  They also readily form very stable oximes and have therefore … Continue reading →

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Fluorous Crown Ethers

Posted on July 7, 2010 by Marv

Phase transfer catalysis (PTC) has been an active area of interest for over 50 years and have now been incorporated into hundreds of industrial processes.  The primary role of these catalysts are to transfer an inorganic reagent from a non-organic … Continue reading →

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Olefin Metathesis and Diels-Alder Reactions

Posted on June 7, 2010 by Marv

One of the best applications of fluorous tags is in diversity-oriented syntheses (DOS).  Since fluorous solid phase extraction (FSPE) is a very general technique, it lends itself well to library and parallel synthesis since there is little method development necessary.  … Continue reading →

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Fluorous and Microwave

Posted on May 14, 2010 by Marv

In Fluorous Technologies’ April Technical Newsletter we highlighted some recent examples from the literature demonstrating the use of fluorous methods in conjunction with other technologies.  One of the other technologies was microwave heating.  While we only showed one example in … Continue reading →

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Fluorous Organocatalyst in Reductive Aminations

Posted on May 11, 2010 by Marv

Last month we highlighted a paper from Profs. Cai and Zhang at Nanjing University and UMass-Boston describing their work using a fluorous thiourea organocatalyst in asymmetric alpha-chlorinations.  Just available online is a new accepted manuscript from Prof. Cai describing a … Continue reading →

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