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Peptide reagents + amino acids

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Fmoc

Boc-ON

F-Z-Osu

Trityl chlorides

Trityl alcohols

CDMT

t-Butanol

Mukaiyama's Reagent

HOBt

Msc chloride   

DCC

Fmoc & Boc-protected amino acids

Z-protected amino acids

  

Msc chloride

 

F-Msc-Cl is a base labile fluorous tag based on the Msc (methylsulfonylethoxycarbonyl) protecting group used for the N-protection of amines.  Overkleeft used the F-Msc group in the N-terminal tagging of peptides synthesized using a Fmoc based SPPS strategy (1).  The F-Msc tagged peptides were purified by either F-HPLC or F-SPE.  The F-Msc group was removed by treatment with piperidine to provide the final peptide.

 

1. de Visser, P. C.; van Helden, M.; Filippov, D. V.; van der Marel, G. A.; Drijfhout, J. W.; van Boom, J. H.; Noort, D.; Overkleeft, H. S. Tetrahedron Lett. 2003, 44, 9013-9016.

 

Rf NAME/CAS# PROPERTIES CATALOG# QTY PRICE
C8F17 1H,1H,2H,2H-perfluorodecyl sulfonylethyl chloroformate (F17-Msc-Cl)  
C13H8ClF17O4S
F017169 Please inquire
    FW:  618.66      
           
           
     
 

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